Sentence examples for planned dose levels from inspiring English sources

Chemotherapy doses were escalated through six planned dose levels (DLs) as shown in Table 1.

The doses of each agent were escalated through six planned dose levels (DLs).

If the MTD was not exceeded within the planned dose levels, the MTD was defined as the maximum dose tested.

If the MTD was not exceeded within the planned dose levels, MTD was defined as the maximum dose tested.

Three patients were subsequently enrolled to each fixed-dose cohort, with planned dose levels of 60, 90 and 120 mg per day.

Patupilone was administered every 3 weeks either as a 20-min infusion (20MI), 24-h continuous infusion (CI-1D) or 5-day continuous infusion (16-h per day over 5 days; 16HI-5D) with planned dose levels of 6.5, 7.0, 7.5, 8.0, 9.0 and 10.0 mg m 2 until disease progression, unacceptable toxicity or withdrawal of consent.

In the SIB HDR brachytherapy plan dose levels were optimized to match the TCP of the 10Gy HDR brachytherapy plan for the PTVDIL and remaining PTVHDR.

We did not plan dose levels 6 8 at the beginning of this trial, because standard doses without concurrent thoracic radiation therapy in Japan were docetaxel 60 mg m−2 and cisplatin 80 mg m−2 at a 3-week interval (Kubota et al, 2002), which corresponded to docetaxel 30 mg m−2 and cisplatin 40 mg m−2 on days 1 and 8 at dose level 5.

This involved the continuous, once-daily dosing of abiraterone acetate to castrate, chemotherapy-naïve patients with CRPC, escalating through five pre-planned dose levels of 250, 500 , 750 1000 and 2000 mg using three-patient cohorts.

All subjects in the first two cohorts completed the study and received all doses according to the study plan but the study was halted before the third cohort received the highest planned dose level of 2800 μg.

Compliance was reported as planned dose taken = 100 × cumulative dose taken/cumulative planned dose.