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Primary exclusion criteria were a history of grade 2 or higher nausea prior to enrollment, previous PALO use, planned administration of MEC on multiple sequential days, and planned administration of cisplatin (CDDP) regardless of dose.
Myelosuppression was recorded in nine patients delaying planned administration in eight of 35 cycles.
A protocol directed ESA dose adjustment according to approved labeling [ 11], based on the most current Hb value measured 1 week previous to the planned administration.
The number of patients was calculated at the time when S-1 administration was stopped or the planned administration dose per day was reduced because of adverse events of S-1.
Other exclusion criteria included receipt of any licensed live-attenuated vaccine within 30 days before study vaccination, any licensed inactivated vaccine within 15 days of study vaccination, or planned administration of any other vaccine not foreseen by the study protocol between Day 0 and Day 21.
Primary inclusion criteria were age of 20 years or older, diagnosis of malignant tumor, no history of chemotherapy (patients who had received LEC were permitted), planned administration of non-AC MEC, and sufficient marrow, renal and kidney function to tolerate chemotherapy.
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Moreover, before DLT was observed in level 1, 8 of 31 planned administrations were omitted due to adverse effects including leukocytopenia, neutropenia, GOT/GPT increase, and severe fatigue.
Germany, Sweden, and other European countries also developed planning administration and law at this time.
The Professional Employer Organization Services segment provides employment administration outsourcing solutions through a co-employment relationship, including payroll, payroll tax filing, HR guidance, 401(k) plan administration, benefits administration, compliance services, health and workers' compensation coverage and other supplemental benefits for employees.
Efforts in post-industrial countries to refine environment and planning administration in the face of unprecedented urban growth have important implications for ecological systems and human quality of life.
Another ambiguous term is the word "treatment," which for radionuclide therapies involving planned repeated administrations may refer to one administration or a series of administrations.
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