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Various structural models suggest a planar adhesion plaque will form that closely links two sides of ER lamellae or tubules, with an intra-lumenal separation between the stapled membranes that from first principles could vary from 10 to 23 nm, depending on the preferred arrangement of trans-aggregating FM4 domains.
Currently in humans the easiest and most widely available nuclear medicine methods in assessing atherosclerotic plaques are visualizations of the peripheral arteries using SPECT or planar scintigraphy.
The three approved agents have a planar chemical structure that is suitable for binding to β-sheets in Aβ plaques.
However, from the ERK1/2 negative feedback hypothesis outlined above, it would follow that as cells cultured on 540 nm deep grooved substrates contain similar numbers of SMAs and more FAs than planar controls, FAK signalling should be up-regulated as more integrin receptors are recruited to adhesion plaques.
It's not so planar".
No plaque.
A planar image seems to become three-dimensional.
This is plaque".
A plaque to read.
Jack drops his plaque.
Both are planar and rugged.
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