Sentence examples for plague strain from inspiring English sources

The patient survived, however, thanks to yet another antibiotic, trimethoprim, to which the plague strain was not resistant.

The researchers now hope to reconstruct the whole genome sequence of the plague strain in these ancient teeth to learn more about the disease, Scholz said.

Furthermore, introduction of the NS gene from an H5N1 HPAIV into an H7N1 fowl plague strain rendered it virulent for mice [41].

"Plague strains are always emerging from rodent reservoirs, causing disease in humans, but what we don't see are the widespread pandemics because now the public health response would be quick and very concentrated to shut that down".

Although the researchers who isolated it say they know of no other occurrences of the resistant bacteria, they note that the genes that confer drug resistance can easily spread to other plague strains, posing a threat of new pandemics of the disease.

By sequencing the genomes, we find that these ancient plague strains are basal to all known Yersinia pestis.

One possible explanation would be the presence of additional virulence factors in historical plague strains, which have been lost from current Y. pestis strains.

The absence of lung infection apparently is not related to a particular strain of the plague bacillus since the Y. pestis strain that currently circulates in Mahajanga was likely introduced from the highlands in 1991, as demonstrated by pulsed-field gel electrophoresis genotyping (Buchrieser et al, manuscript in preparation).

Our findings suggest that the virulent, flea-borne Y. pestis strain that caused the historic bubonic plague pandemics evolved from a less pathogenic Y. pestis lineage infecting human populations long before recorded evidence of plague outbreaks.

In our previous study, we identified a 383bp region (DFR4) specific for the Y. pestis strains from plague Focus B in China by suppression subtractive hybridization (SSH [21].

Altogether, the data indicate that loss of a single Ybt-synthetic enzyme in a fully virulent Y. pestis strain can account for the avirulence observed for Pgm– or Ybt– strains in bubonic plague infection models, and support the hypothesis that the Ybt system provides the iron required by the bacteria during the early steps of the infection.