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Molecules of interest include macrolides, whose biological importance, lack of natural resources, and interesting structure placed a challenge among the scientific community for their total synthesis.
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The idea of a referendum is designed to go above the heads of politicians and to place a challenge to the people of Northern Ireland: to find a way to deal with the past or face the prospect of a highly unstable political settlement.
It also places a challenge on control system architecture to entertain the constraints of procurement slicing and meeting the overall functional requirement.
History has placed a great challenge before us.
Both these mandates have placed a huge challenge in the lap of the already ailing automotive industry.
But Johnson placed an indirect challenge to Yankee fans: either be with him, or against him.
Ferdinand was right behind him and Old Trafford held its breath when the defender took the plunge, placed an awkward challenge and Tevez tumbled to earth.
Davies, who has taken 253 first class wickets at an average of 22.63, acknowleged that with an increase in numbers comes an increase in competition for places - a challenge he is ready for.
United's defence was poor – vulnerable all night and breached twice by Moyes' players failure to place a telling challenge when it mattered.
Mayor Michael R. Bloomberg's proposed cut of 1,900 police officers will place a significant challenge before Police Commissioner Raymond W. Kelly as he works to reduce crime and prevent possible terrorist attacks, say current and former police officials.
Morgan dribbled past two defenders, kept her balance against a challenge and placed a left-footed shot inside the left post from 12 yards.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com