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Each female rat has a preferred pacing interval, and females develop conditioned place preferences for paced sex versus nonpaced sex.
In other animals, intra-VTA heroin-induced place preferences were challenged with systemically applied alprazolam (0.125 mg/kg IP).
But it's not as big a step as it may appear, because it leaves in place preferences for what admissions officers refer to as "legacies" and "development cases".
The findings indicate that female rats develop conditioned place preferences for paced sex and for sex in which the male is removed at her preferred interval.
Hall FS, Li XF, Sora I, Xu F, Caron M, Lesch KP, et al. Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions.
Following a priming cycle of cocaine conditioning (dashed line), both sets of mice demonstrated reinstatement of a similar magnitude of place preferences (bars to right of dashed line).
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Place preference conditioning with methylphenidate and nomifensine.
produced a dose-related place preference.
Morphine produced a significant place preference.
In the conditioned place preference (CPP) test, inactivating RACK1 markedly reduces morphine-induced conditioned place preference.
Pharmacologic characterization of nicotine-induced conditioned place preference.
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