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For example, in modelling curves using splines a 'roughness penalty' is employed to place preference on simple, smooth functions [ 16].
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Importantly, the new strategy also places preference on creating a "net benefit" where possible.
The effect of locomotor activity on the test day was assessed with regard to its effect on place preference for all strains except 129.
The study explores whether differences in the variety and organization of the spaces of school facilities have an impact on the place preferences of students and whether students are aware of the reasons for their preferences.
Observed memory deficits were likely independent of differences in reward motivation, as conditioned place preference for the palatable food used on both tasks was similar between the adolescent social defeat group and control.
The behavioural paradigms used here such as the dynamic cold plate and the thermal place preference test on freely moving animals implemented the knowledge on the effects of oxaliplatin by providing robust and clear quantification of the hypersensitivity to cold that has not been previously reported.
Mice that did not obtain a place preference based on these criteria were removed from the study.
In a second series of experiments, we assessed the effects of selective prefrontal cortical NE depletion on conditioned place preference (CPP) and on conditioned place aversion (CPA) induced by rewarding and aversive natural stimuli respectively.
The testing of place conditioning was done in the absence of any drug, suggesting that the place preference effect depends on learned associations between drug-paired environmental stimuli and drug-induced states.
The conditioned place preference paradigm took place on 5 consecutive days using the biased apparatus.
One widely used method for assessing reward sensitivity in animals that avoids this particular ambiguity, conditioned place preference (CPP), is based on ideas of Pavlovian conditioning.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com