Exact(7)
The surface modification on the PLA/HA scaffold was directly observed using SEM. Figure 6 shows that HA crystals were evenly distributed on the PLA structure – not only on the surface of the scaffold, but also in the deeper structure around macropores in the scaffold due to vacuum conditions during modification.
The influence of the PLA initial chemical structure (stereosequences) on the degradation process was clearly evidenced and the time dependence of the relative amount of l-lactic, d-lactic, and meso-lactic units within the PLA structure was estimated.
Attenuated total reflectance Fourier transform infrared spectroscopy and x-ray photoelectron spectroscopy showed the bounding of fluorines in the PLA structure, which leads to the increase in hydrophobicity of PLA.
In the Pla structure, L1 residues D33-R38 form a network of hydrogen bonds.
K262 and N263 are located in the very tip of L5, and in the Pla structure, both residues are in contact with L4.
Altogether, the Pla structure seems to allow close approach by the substrate, and the active site to be well stabilized by interloop interactions.
Similar(53)
Calls could be elicited at standard stimulation currents, and no lesioning of PLA structures by iontophoretic currents could be detected.
The PLA support structure was selectively removed, and the water soluble PVA structure was used for creating a 3D vascular network within a customized extracellular matrix (ECM) targeting the stiffness of the liver and with encapsulated hepatocellular carcinoma (HepG2) cells.
In this study, BMS is made of polylactide (PLA) lattice structure and polyurethane (PU) foam for an enhanced impact resistance.
Combretastatin A4 (CA4) was used as the model drug loaded in PLA (core structure) to test the thermo-sensitivity of the core shell fibers.
Our results do not give a direct roadmap to the Pla molecular structure but rather describe how easily the substrate specificity of an omptin can evolve and how functions that are pathogenic in a novel environment can be gained.
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