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The pK of the −SH group is 10·6.
The pK and pK′ (polarographic pK) of this substance are calculated both polarographically and spectrophotometrically.
This review article discusses current understanding of PK of therapeutic mAb and Fc-fusion proteins.
Pharmacokinetic (PK) of drugs in critically ill patients could vary from the general population.
The main pharmacokinetics (PK) of colistin are presented in Table 1.
On the basis of these dissolution functions, pharmacokinetics (PK) of six model drugs was predicted well.
Likewise, oral PK of furosemide was found to be predominantly governed by the gastric emptying patterns.
These results clearly indicate that the variable region does also influence IgG-FcRn interactions, thus impacting PK of a mAb.
First, process capability index C pk of the current process was computed which was found less than 1.
Glycosylation of a mAb or Fc-fusion protein can have a significant impact on the PK of these molecules.
The pharmacokinetics (PK) of a mAb is best described by "What the body does to the drug".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com