Based on the basic understanding of the process and its parameters, a pivotal attempt is undertaken to weld alloy steel tubes of boilers with specially made MIAB welding equipment (MD1).
These results were similar to those observed in pivotal RCTs undertaken in women with postmenopausal osteoporosis.
These changes in BMD were comparable in magnitude to those observed previously in pivotal RCTs undertaken postmenopausal women.
Although direct evidence about their non-vertebral anti-fracture efficacy are lacking, the effects of bisphosphonates, denosumab, teriparatide, and strontium ranelate on surrogate outcomes (BMD and markers of bone turnover) were similar to those reported in pivotal RCTs undertaken in postmenopausal women, in which vertebral and non-vertebral anti-fracture efficacy have been clearly demonstrated.
In 1994 Tracey Emin undertook a pivotal roadtrip across America with her boyfriend Carl Freedman; alongside them was an Edwardian armchair, inherited from her grandmother.
If the intention is to use autologous human stem cells such as mesenchymal cells, should the pivotal animal studies be undertaken using human cells in immune compromised animals or animal cells that are the nearest equivalent to the human therapeutic?
The relative rarity of cardiovascular damage in the clinic normally means that a strong safety signal will only emerge in large pivotal trials or investigations undertaken through postmarketing surveillance.
The US Congress is undertaking….
In this scenario, the oral multikinase inhibitor sorafenib is the only drug which is in two phase III pivotal, placebo-controlled clinical trials undertaken in patients with advanced HCC in the Western countries and in the Asia-Pacific area has been able to induce a statistically significant improvement of overall survival [ 6- 8].
The manner in which increasingly interested foreign firms were allowed to undertake exploration and mining became a pivotal political issue in Greenland in the early 21st century.
The DNC hack, revealed by The Washington Post in June 2016, was considered a pivotal event in several actions believed to be undertaken by the Russian government to meddle in the U.S. presidential election that year.
