Sentence examples for pivotal subset of from inspiring English sources

Regulatory T cells expressing the transcription factor FoxP3 represent a pivotal subset of Tregs for dominant control of adaptive immune responses in the periphery [49], [50].

We suggest that these effects of Mef2ca 4–5–6 are attributable to its ability to activate, directly or indirectly, a specific subset of pivotal genes in gastrulation.

These findings define a pivotal role for cyclin D1 in a subset of mammary cancers in mice and imply a functional role for cyclin D1 overexpression in human breast cancer.

This pivotal cardiac marker is expressed within a substantial subset of the differentiating population, but not in all cells and it remains expressed for the life of the cardiomyocyte in vitro and in vivo.

This study provides insights into a novel mechanism, which is useful for the generation of drugs targeting stability and bioactivity of a small subset of chemokines, however, showing a pivotal role in a number of inflammatory conditions.

These findings define a hitherto unknown mechanism of action for arginine methylation in regulating translation of a subset of mRNAs including those encoding pivotal leukemogenic transcriptional regulators MLL1 and MLL4.

To date, however, no investigations have been carried out on cancer stem cells (CSCs), a subset of cancer cells thought to play a pivotal role in tumor development as well as in tumor pharmacological resistance [ 15].

T regulatory (Treg) cells are a recently discovered subset of T-lymphocytes with potent suppressive activity and pivotal roles in curtailing destructive immune responses and preventing autoimmune disease.

We investigated whether a subset of monocytes that express TIE2 (TIE2-expressing monocytes, TEMs) and are pivotal to neovascularization in tumours may also have a role in the revascularization of the critically ischemic limb.

These pivotal proof-of-concept studies used various subsets of pre-CC lines from either the CC-UNC or CC-TAU populations, some of which have since become extinct.

Thus, palmitoylation tunes NCX function in only a subset of cellular circumstances, specifically circumstance of cell stress in which exchanger function can be pivotal for cell survival or demise.