(On Wednesday, Rosenstein's role only looked more pivotal: reports said that, just last week, Comey had come to him to ask for more resources for the Russia probe).
In 2007, he led an international team of researchers in preparing nine pivotal reports that led to the 2008 listing of polar bears as a threatened species under the US Endangered Species Act.
In June 2013, Jonathan Zittrain co-authored also a pivotal report produced by the Council on Foreign Relations, directed by Adam Segal and involving also Professor Anne-Marie Slaughter (New America Foundation) -- "Defending an Open, Global, Secure, and Resilient Internet".
But the single most important point to take home from this pivotal report, I believe, is that even though caste-based discrimination may have arisen in Hindu society, it is not intrinsic to Hinduism.
In a pivotal report [ 16], mice pretreated with simvastatin and rendered septic by cecal ligation and perforation were found to exhibit a mean survival time close to four times that in untreated control animals.
The prospective U.S. pivotal study reported a 5-year capsular contracture risk rate of 3.3% for augmentation subjects and 9.6% for reconstruction subjects [ 6].
The ratio of adverse events leading to death was 1.6% in our study compared to 2.6% and 2% in the pivotal study reported by Hurwitz et al. and by the BEAT study respectively [ 13, 24].
A pivotal study reported a benefit in overall survival and locoregional control in patients with localised head and neck cancer who were treated with both radiation and cetuximab, a monoclonal antibody against epidermal growth factor receptor (EGFR), over patients treated with radiation alone (Bonner et al, 2006).
This pivotal study publication reported on two parallel, multicenter, randomized, double-blind, Phase III clinical trials.
Maddams et al (2009) have previously reported a pivotal study indicating that around 2 million people were alive in the UK following a diagnosis of cancer at the end of 2008, and that this figure will rise by 3% each year.
The median PFS reported in the Phase II RTD study (10.4 months) was similar to that reported in the pivotal study (all patients: 9.2 months, treatment-naïve: 11.1 months), and resembles those of the current standard metastatic RCC therapy sunitinib (11 months in first-line).
