Sentence examples for pivotal mode from inspiring English sources
In contrast, Halicka et al. found that the anti-oxidant activity of metformin is functionally linked to enhanced genomic stability, the pivotal mode of action underlying the anti-aging effects of metformin.
PCC, AG and ACC are considered to be pivotal in default mode network (DMN), with a high activity correlated to the rest and reactive deactivation during most tasks where the attention is directed externally.
It is concluded that boron probably is complexed with hydroxylated species in biologic systems, and that inhibition and stimulation of enzyme and coenzymes are pivotal in its mode of action.
The central role taken by global firm subsidiaries was pivotal to a new mode of interrelationship between the various business and non-business actors in the region.
The precuneus is a pivotal region of the default mode network, which was particularly sensitive to the cognitive states in self-referential tasks [48].
The precuneus/posterior cingulate cortex, which has been associated with pain sensitivity, plays a pivotal role in the default mode network.
Post hazard surveys indicate connections that form the load path from sheathing to framing to foundation play a pivotal role in the failure modes of these non-engineered structures.
In the library syntheses, the binding modes of each pivotal compound were determined and confirmed by X-ray crystallography and the library was strategically designed by structure-based computational approach not only to obtain a more active compound but also to obtain informative Structure Activity Relationship (SAR).
Leveraging a crossover within-subjects design, we demonstrate that pivotal brain regions involved in the default mode and limbic regulatory centers have disrupted functioning following a night of restricted sleep compared to a night of "normal sleep".
This finding represents a pivotal clue in unraveling a possible epigenetic mode of arsenic-induced disease.
For the risk assessment approach with regard to carcinogens, the mode of action is of pivotal importance.
