Sentence examples for pivotal interplay from inspiring English sources

Knowledge of fracture healing has advanced; the complex and pivotal interplay of biology and biomechanics is recognised and the management of fractures and, consequently, osteotomies have evolved.

Furthermore, Dicer and TARBP2, along with p53, serve as a target for the let-7 family miRNAs, suggesting a pivotal interplay between p53 and let-7 in miRNA biogenesis.

A deep analysis of such interplay is pivotal in order to build vegetation anamnesis and make sound projections.

It is now regarded as a pivotal factor in the interplay between neuroendocrine function and the immune system [ 11, 12].

CD40 ligand (CD40L), or CD154, is expressed on activated T lymphocytes, and through interactions with its receptor CD40, plays a pivotal role in regulating the interplay between T cells and other cell types [ 1– 3].

In contrast, USP7 (also known as HAUSP), which was originally identified through an interaction with a Herpes simplex virus immediate-early gene (Everett et al, 1997), is credited with a pivotal, but complex function in the interplay between p53 and MDM2 (Li et al, 2002, 2004; Cummins and Vogelstein, 2004; Cummins et al, 2004; Brooks et al, 2007).

Just as the site- and time-dependent context of its release, the complex interplay between TNFα receptor subtypes is pivotal in defining the actual effect of TNFα [ 3].

The interplay between tumor cells and their microenvironment plays a pivotal role in tumor development and progression.

These findings uncover the complex and diverse interplay between PDAC tumors and the stroma and demonstrate the pivotal role of xenografts for drug discovery and relevance to PDAC.

Abscission is a coordinated process tightly regulated by the interplay of several factors, among which auxin and ethylene play a pivotal role [ 1, 2].

Although most of the accessory proteins do not seem to play pivotal roles in viral replication, they might still be important for the virus-host interplay and for pathogenicity.