Sentence examples for pivotal interactions from inspiring English sources

For PPIs that are mediated by the formation of an intermolecular β-strand, the situation is different, with most pivotal interactions being specific hydrogen bonds between the proteins augmented by some side chain interactions that are located in usually shallower subpockets.

Furthermore, we discovered the Rho-GTPase homolog SmRho1 of S. mansoni as a first pivotal interaction partner of SmDia.

The local immune response to bacteria, including live BCG, is complex, but the presentation of bacterial antigens by APC to T-helper cells is the pivotal interaction (Alexandroff et al, 1999).

In the BRCT domains of all three polymerases, α-helix 1 is pivotal to interactions with the end-joining factors, with structural variations in the interaction surface observed among the three.

The aim of this study was to define the pivotal molecular interactions involved in recognition and lysis of RMS cells by resting and activated NK cells.

However, this activity is not conserved in yeast cells and the hClp1 ATP-binding homologous domain is pivotal for interaction with Pcf11 [74].

In this scenario, molecular structures of HS, for example, sulfation pattern and chain length, are pivotal in interaction between endothelial cells and leukocytes as well as with the soluble inflammatory cytokines.

This author also underlined three principles for designing user-friendly interfaces: 1) human-machine interaction is pivotal; 2) this interaction evolves through use; and 3) user should be the key informant.

It is likely that the orexin system is pivotal in these interactions between sleeping and feeding.

The immune system is pivotal in mediating interactions between the host and the microbiota that shape the intestinal environment [ 5, 6].

It could be shown that for Pc several charges are pivotal for the interaction.