Sentence examples for pivotal in the regulation of from inspiring English sources
The transcription factor NF- κB in particularly is pivotal in the regulation of inflammation.
These compounds are pivotal in the regulation of cell proliferation, angiogenesis, immune function and inflammation, which may all contribute to the development and progression of neoplasms [ 1].
The vascular endothelium is the largest organ of the body and comprises a highly dynamic single layer of endothelial cells (ECs) that are pivotal in the regulation of vascular tone and that have essential anti-thrombotic and barrier functions.
In addition, angiotensin (Ang) II is pivotal in the regulation of blood pressure, and stimulation of PT transport may play a critical role in Ang II-mediated hypertension [ 5, 6].
The NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) family of transcription factors are pivotal in the regulation of a wide variety of biological processes [ 60- 63].
A large body of evidence supports the suggestion that SREBP1 (sterol regulatory element-binding protein 1) is pivotal in the regulation of milk fat synthesis in mouse [ 7] and cow [ 83].
Small noncoding RNAs play a pivotal role in the regulation of gene expression, and are key regulators of animal development.
Over the last 10 years, miRs were also identified as the regulators of inflammatory signals and played pivotal roles in the regulation of bone biology [ 20– 20].
microRNAs are the potential regulators, widely known for playing a pivotal role in the regulation of various biological as well as metabolic processes.
Finally, we explored whether the PI3K/AKT pathway, which plays a pivotal role in the regulation of MM cell proliferation, survival and drug resistance, could regulate miR-29b-Sp1 loop.
It is a key regulator of energy homeostasis and plays a pivotal role in the regulation of genes involved in fatty acids oxidation, metabolism of lipoproteins, gluconeogenesis, and synthesis of ketone bodies (Mandard et al. 2004).
