Sentence examples for pivotal functions of from inspiring English sources

This prompted us to investigate whether SSTRs affect pivotal functions of keratinocytes i.e. proliferation and migration and whether we can find receptor subtype specific differences.

Here, we review recent progress on subtype-specific subcellular localization, participation in signaling cascades, and the pivotal function of α1-ARs, as delineated through studies on genetically engineered animals.

All of these results illustrate the pivotal function of CCL19 in clinical settings.

The second pivotal function of storing genetic information as a DNA protein complex is the additional layer of regulation that this feature provides.

An in vitro study has highlighted the pivotal function of normal Htt in the differentiation of embryonic stem into hematopoietic cells.

Here, we used conditional Glis3-deficient mouse models to demonstrate the pivotal function of Glis3 in controlling insulin gene expression in the adult pancreas in vivo.

Production of glycine inside the mitochondria, required for heme biosynthesis and further production of one-carbon units by the glycine cleavage system, is also a pivotal function of SHMT2.

These data point towards a pivotal function of IFNβ producing microglia in the orchestration of phagocytosis of myelin debris by not only neighboring microglia but also immigrating phagocytes in CNS autoimmunity.

Despite different experimental conditions (infectious doses, inoculation route, time after infection), a common feature of all models is the occurrence of Mikulicz cells, confirming the pivotal function of these cells in the infectious process.

Given pivotal function of p53 in tumour suppression, it is no surprise that the p53 gene is the most frequent target for genetic alterations in human cancers (Hollstein et al, 1996).

The more vigorous angiogenesis by FPR+ GBM cells was further shown by higher microvessel density in tumours formed by such tumour cells, indicating a pivotal function of FPR in enhancing the angiogenic and vasculogenic process in GBM.