Sentence examples for pivotal for regulating from inspiring English sources

These findings may represent a general mechanism for the acquisition of new epialleles in somatic cells, which are pivotal for regulating gene expression in plants.

It has been shown that both the histone tails and globular domains are subjected to a diverse array of the posttranslational covalent modifications (e.g. acetylation and methylation), and that such modifications are pivotal for regulating chromatin dynamics and transcriptional output of the gene/genome (1 4).

Platelet secretion is undoubtedly of pivotal importance for regulating not only canonical platelet functions, but also mediating their impact on other cells, and understanding platelet secretion may have consequences reaching far beyond the 'platelet field'.

SPL is a pivotal enzyme regulating S1P intracellular concentrations and a promising drug target for the design of immunosuppressants.

However, part of the ABA is catabolic inactivated, which also plays a pivotal in regulating the intensity of ABA signal.

The CDK1-cyclin B1 complex is pivotal in regulating the G2/M phase transition and mitosis.

The cdc2-cyclin B kinase is pivotal in regulating this transition.

Taken together, these data suggest that COUP-TFI and COUP-TFII play a pivotal role in regulating ion channel genes responsible for unique electrophysiological phenotype of human atrial cells.

The calcium-sensing receptor (CaSR) plays a pivotal role in regulating systemic Ca2+ homeostasis and is a target for drugs designed to treat certain disorders of bone and mineral metabolism.

These genes possibly play pivotal roles in regulating the expression of genes encoding enzymes required for the cuticle sclerotization process.

Biologically, DTNBP1 is a strong candidate for schizophrenia pathogenesis as it is thought to play a pivotal role in regulating the glutamatergic system [ 7, 8].