Sentence examples for pivotal for interaction from inspiring English sources

However, this activity is not conserved in yeast cells and the hClp1 ATP-binding homologous domain is pivotal for interaction with Pcf11 [74].

It could be shown that for Pc several charges are pivotal for the interaction.

In agreement with this hypothesis, the different action of ceramide on SGK-1 and AKT-1 may be, at least in part, dependent on the absence of pleckstrin homology (PH) domains in SGK-1, which is pivotal for the interaction of PDK-1 and AKT-1 with plasma membrane phosphoinositides, modulating its activation.

Since W74 of IRAK-M is pivotal for IRAK-4 interaction [ 13] it appears that the functionality of IRAK-M in the inhibition of TLR5 mediated IL-8 in these epithelial cells is independent of its interaction with IRAK-4.

As shown in Figs 2 and 3, the Gab2/Grb2 interaction is pivotal for the recruitment of this docking protein to most, if not all receptors and consequently this novel regulatory mechanism should have broad implications for diverse signalling systems.

Here we report that the female gametophyte-expressed glycosylphosphatidylinositol-anchored protein (GPI-AP) LORELEI and the seedling-expressed LRE-like GPI-AP1 (LLG1) bind to the extracellular juxtamembrane region of FER and show that this interaction is pivotal for FER function.

These interactions are pivotal for the integration of the dynamic mitochondrial network into the architecture of eukaryotic cells.

Understanding these missing regulatory interactions is pivotal for future attempts to synthetically engineer T. reesei for enhanced cellulolytic functions.

Lipid protein interactions are pivotal for myelin maintenance, since they regulate the molecular organization within the myelin sheath.

These interactions are pivotal for maintaining accurate replication of histone methylation patterns in newly replicated chromatin and in the subsequent fidelity of gene expression.

SUMOylated ESET-Oct4 interaction is probably pivotal for both the establishment of pluripotency in the ICM and its maintenance in ES cells.