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This was an early pivotal experiment in EC miRNA biology.
Since the pivotal experiment by Orò [ 9] on the synthesis of adenine from HCN, numerous studies were devoted to assess the role of this compound in the origin of primordial nucleic acids [ 10].
The pivotal experiment performed by Woods et al. (4) in the late 1970s showed that intracerebral infusion of insulin in baboons reduced food intake and body weight and paved the way for intense scientific investigation over subsequent years by highlighting the key role of insulin at the central nervous system (CNS) level.
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However, certain pivotal experiments done exclusively on C57BL/6J in the past should be validated on a progeny of an F1 cross with a distant strain, to verify that these discoveries do not belong to "parallel universes" of Black Six biology.
The pivotal experiments supporting the AGM's role as an autonomous source of dHSCs includes short-term ex vivo organ culture of the AGM, fetal liver and the yolk sac [ 63].
This result (i.e. the induction of Bet v 1-specific IgG without inclusion of Bet v 1-specific T cell epitopes in the vaccine) can be explained according to the hapten-carrier principle described by the pivotal experiments of the Nobel laureate B. Benacerraf that led to the discovery of T cell-dependent antibody production 2, 3.
A former computer programmer at Genentech has agreed to pay $76,000 to settle charges that she profited from inside information about a pivotal drug experiment, the Securities and Exchange Commission said today.
During the winter of 1995 96, Wilmut was involved in three pivotal cloning experiments conducted at Roslin.
The ability to localize the oximetry probe accurately is pivotal to the experiment.
This experiment demonstrates the pivotal role of OCT4 in maintaining the self-renewal characteristics of these cells.
To gain more knowledge on the therapeutic potential of the NBD peptide in humans, we extended the experiments to another pivotal cell type in the pathogenesis of RA, the macrophage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com