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Despite pivotal developments in endocrine therapy and chemotherapy, resistance to therapy remains a key limitation in the management of invasive breast cancer.
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The arts minister, David Lammy, said it "could represent a pivotal development for culture in the UK".
The Center for Responsible Lending's Keith Corbett, for instance, called Google's announcement a "pivotal development" for fairness in financial services.
The financing announced on Wednesday could prove a pivotal development in the intense debate over Tesla's future.
It's not a massive amount of games but it represents a pivotal development in the positive perception of the league in the UK.
While the sentiment surrounding the company has recently been positive, "the financing announced on Wednesday could prove a pivotal development in the intense debate over Tesla's future," Mr. Eavis says.
The News Corp./NBCU venture could prove to be a pivotal development in the growth of the embryonic market for online video advertising.
An early pivotal development was a widely circulated 1971 memo written for the U.S. Chamber of Commerce by the soon-to -be appointed Supreme Court Justice Lewis Powell.
incorporated in his music elements of folk music, created evocations in his 'night music', and used exotic scales and new tonal resources, all which were pivotal to developments of more recent music.
Taking into account carbon sequestration and release in both terrestrial as well as the aquatic environments is pivotal for development of comprehensive climate mitigation strategies [6].
Hope is believed to be beneficial for vocational pursuits, but the question of how and why hope is related to pivotal career development variables remains largely unaddressed.
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