In concert with previous findings on the miRNAs and PH, this study will undoubtedly open up new pipelines of research and novel therapeutic approaches for this disease.
If the pipeline model of research use were correct, it would be possible to demonstrate the impact of research on policy and the value of research would be judged on its contribution to policy and its quantifiable impact [ 25].
This week GSK unveiled its crown jewels: a full pipeline of compounds in research and development, the result of a £2.6 billion ($4.5 billion), 16,000-researcher-strong effort.
On Thursday, Sanofi also said it was rebuilding its pipeline of drugs in research and development.
At about 2% of sales, this is considerably more than rivals are spending: in 2007 Danone spent about 1% of its sales on R&D, and Kraft spent about 1.2%.Richard Laube, the head of Nestlé's nutrition business and a former pharmaceuticals executive, describes a "pipeline" of some 75 research projects.
Another area that is becoming increasingly important is the translation of basic science research findings into clinical applications, and there is a growing need for physician scientists, says Alan Trounson, president of the California Institute for Regenerative Medicine CIRMM)."We see an entire pipeline of basic science research through translation and eventually to the clinic.
He devoted his PhD to battling NTDs; however, he judges that the current outlook for the current pipeline of academic NTD research trainees is not good.
Consequently, these databases have become an integral part of many processes and pipelines in various fields of research and development.
In the authors' experience the trend is clear in bioinformatics — workflow tools are getting increasingly more powerful, user-friendly, and hence more frequently used and appreciated for automation and creation of research pipelines.
Step 1 (i.e., going from data to a filtered complex) of the PH pipeline is an active area of research, but many sparsification techniques (see, e.g., [97, 112]) for complexes have yet to be implemented, and more research needs to be done on steps 1 and 3 (i.e., interpreting barcodes; see, e.g., [130, 136, 143]) of the PH pipeline.
