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To pinpoint the defect in daughter abscission at the molecular level we evaluated the development of the cytoskeleton in the MORN1 mutant using a battery of markers to highlight different aspects of the budding, maturing and mature cytoskeleton (Fig. 5).
At present, we have not pinpointed the cell cycle defects to any distinct phase of the cell cycle, however, preliminary data from UPF2 null lymphocytes suggest that loss of NMD in these cells results in an early block in S-phase (JW and BTP, unpublished observations).
Deficiencies in several respiratory complexes have been reported in PINK1 deficient cells (Gautier et al, 2008; Gegg et al, 2009; Hoepken et al, 2007; Piccoli et al, 2008); however, this study pinpoints the respiratory defect specifically at the level of complex I activity.
In addition, to try to pinpoint where the defect in AP2 mutants might lie, we analyzed more sections and performed a 3D reconstruction of a synapse from the apa-2 apm-2 double mutant.
The CBS News survey pinpointed the same conflict.
The Washington Post pinpointed the bands' appeal.
She has not pinpointed the closing date.
Just as important, they pinpointed the culprits.
He pinpointed the Old Course and Claret Jug.
"We have not pinpointed the cause yet.
Experts haven't pinpointed the exact cause.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com