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In all three p27 genotypes, the values of PIN incidence are close in placebo- and 9cRA-treated animals.
Whilst prostates of Spry1−/− mice had a similar total PIN incidence as Spry1+/− mice, they displayed a significantly lower incidence of HGPIN.
That all Spry2+/− and Spry2−/− prostates assessed displayed PIN pathology with Spry2−/− mice prostates having the greatest total PIN incidence, the highest levels of HGPIN, and the most proliferative epithelial cells than all other mice studied supports this.
Similar(57)
We formally illustrate by modeling silica bilayers as body–hyperpin systems and cross-linking microfibrils as pinned line-incidence systems.
However, there was no significant difference in infection rates, rates of pin loosening, or incidence of higher grade infections on the Checketts Otterburns scale.
Our results compare favorably to previously published figures with an overall pin track sepsis incidence of 22.7 % (52 out of 229) observed in this series.
First, the addition of the 6.5 mm antirotation hip pin reduces the incidence of implant cut-out and the rotation of the cervicocephalic fragment.
This improved fixation translated into significantly lower rates of osteolysis; an 18 times lower incidence of pin loosening [9] and a decrease in pin site infection when compared to uncoated pins [11, 17, 18, 19, 20, 21, 22, 23, 24, 25].
The incidence of pin site infections reported in the literature varies from 4.5%to71%1% [ 57] and pin tract infection varies from 10%to50%0% [ 58].
Parameswaran et al. [3] found that the type of fixator had an effect on the incidence of pin site infection, with monolateral and hybrid fixators showing a much higher incidence of pin site infection than ring fixators.
The overall incidence of pin track sepsis was 22.7 %.
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