Sentence examples for pick body from inspiring English sources
noun
One of the spherical aggregations, caused by a build-up of tau proteins, found in the neurons in cases of Pick's disease.
Argyrophilia with the Campbell Switzer method [ 122] is helpful for more precise and straightforward definition of Pick body.
In patients with FTLD-tau, tau-immunoreactive neurons and neurites were observed throughout the hypothalamus, with occasional Pick body inclusions (see inset in Fig 3).
Authentic Pick bodies in Pick body disease were more solid than pretangles on LM, where abundant tau-positive fibrils, 15 nm in diameter, were randomly arranged without forming PHF [ 19].
The NFTs of progressive supranuclear palsy and corticobasal degeneration are principally or exclusively made of 4R tau [ 276], while Pick body contains exclusively or preferentially 3R tau [ 39, 40].
It comprised 12 bvFTD, 6 with FTLD-tau Pick body inclusions and 6 with FTLD-TDP motoneuronlike inclusions (type 2) 14 without additional neuropathologies, and 6 healthy controls free of significant neuropathology (Table 1).
On the other hand, Campbell Switzer method labels Pick bodies but not CBD/PSP-related lesions [ 120, 122].
Most sporadic tauopathies (including corticobasal degeneration and progressive supranuclear palsy) have predominant 4R-tau deposition (Sergeant et al., 1999); however, Pick bodies contain predominantly or exclusively 3R-tau (de Silva et al., 2006).
About 45% cases contain insoluble tau proteins in their brains in the form of intraneuronal neurofibrillary tangles or Pick bodies [ 28, 30]: many such cases are associated with mutations in the tau (MAPT) gene (see [ 19] for review).
Pick's disease: dementia progresses gradually and is marked by what "Pick bodies".
The Colonel is over here with a picked body of anti-aircraft men which is touring the camps and giving demonstrations for the benefit of American gunners.
He chose the boat-race crews - "a picked body of athletic men" - and asked how many had been born of cousins.
