Exact(35)
A study of PIB in HIV-positive individuals found that cognitively impaired patients with HIV do not show high PIB binding (although some showed low levels of CSF Aβ1-42), suggesthat that PIB may distinguish HIV dementia from AD, a diagnostic dilemma that will become increasingly relevant with an aging HIV-positive population [ 86].
She said that if the House passes the PIB in the coming weeks, "we need to move quickly" to obtain any necessary changes before it becomes law.
When the Heath government wound up the PIB in 1971, Mortimer served as a board member of the London Transport Executive until Labour returned to power in 1974 and his friend Michael Foot, appointed employment secretary, asked him to run the newly established Advisory Conciliation and Arbitration Service (Acas).
Hundreds of birds have been left covered in polyisobutene (PIB) in two incidents on the south coast this year.
Macroporous gels with aligned porous structures were prepared by solution crosslinking of butyl rubber (PIB) in cyclohexane at subzero temperatures.
The authors proposed that AV-45 ROI SUVr included local non-specific white matter uptake, reducing the specificity of the findings compared to PiB in patients.
Similar(25)
Retention of 11C-PiB in the cortex correlates with the distribution of insoluble deposits of Aβ [1] and has been investigated extensively as a biomarker for Alzheimer's disease (AD) [2] and used as an endpoint in interventional trials [3, 4].
Similarly, additional validation is also needed for tracers with potentially very high first-pass lung retention, such as 11C-PIB in studies of cardiac amyloidosis and some tracers of highly lipophilic drugs.
A 2-year follow-up study with C-PIB in AD patients revealed at group level consistent stable fibrillar Aβ levels in the brain [ 32].
Plaque load was determined by calculating the percent area labelled either immunohistochemically (Aβx 40, Aβx 42, 6E10) or histofluorescently (6-CN-PiB) in tissue sections.
While there are more publications on the use of C-PIB in PET imaging of brain amyloid, this compound has only recently completed an FDA quality phase 3 study.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com