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Since excess calcineurin activity can lead to β-cell dysfunction and death (Bernal-Mizrachi et al., 2010), often involving ER stress and apoptosis, this combination of PKA activity and limited access to CaM may help constrain local calcineurin signals within physiologically permissible limits.
Similar(11)
Permissible Acts, Unjust War?
Is capital punishment permissible?
"I mean physiologically," he added.
An "encounter" would be permissible.
Only American gin is permissible.
Were defensive wars permissible?
That's permissible.
And was that motivation permissible?
Physiologically, it's like your drug.
Physiologically and psychologically, we are hunter-gatherers".
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