You need to get the horse as physiologically normal as you can.
And in a web search, most sources I found thought values up to 1,200 mOsm/kg were still in the physiologically normal range and that children varied more than adults.
Only a few examples are necessary to illustrate the point: (1) It is physiologically normal for an individual, 15 to 20 minutes after eating a meal, to have a high blood sugar content.
Physiologically, normal electrolyte concentrations were used as the starting inputs for the model.
In physiologically normal human skin, SDF-1 is constitutively and highly expressed in the dermal fibroblasts.
Since RG7356 is not cross-reactive with murine CD44, studies in mice do not provide any information regarding accessible binding sites in physiologically normal organs.
In tissue engineering, inhibition of the cell contractile response is critical for the regeneration of physiologically normal tissue rather than scar tissue.
Another study identified tumor necrosis factor superfamily-15 (TNFSF15), an endogenous suppressor of neovascularization, plays a critical role in the physiologically normal ovary but is lost in ovarian cancer (Deng et al., 2012).
Consequently, although pH increased slightly in the post-dialyser plasma (Table 2), it did not return to physiologically normal levels of 7.35 7.45, since the chloride resulted in a metabolic acidosis.
On the other hand, we expected that VEGFR-mediated intracellular 177Lu accumulation would lead to a dose-dependent radiotoxicity, which would be more pronounced in VEGFR-overexpressing tumor endothelial cells relative to the cells with physiologically normal levels of VEGFR.
Physiologically normal concentrations of the markers were selected as logic 0 values of the input signals, while their abnormally increased concentrations, indicative of various injury conditions were defined as logic 1 input.
