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The expression of cyclin D1 in B-cells in which the protein is physiologically absent, is supposed to be causal in the transformation process.
They recognize RNA species harboring 5′-triphosphate or diphosphate ends and/or double-stranded features (5′(p ppdsRNA) [ 3– 7] that are physiologically absent from the cytosol (see [ 2] for review).
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A tendency to dimerize was absent in the entire range of physiologically relevant concentrations (Figure 2B).
Ultra-large VWF multimers (ULVWF) are physiologically present in endothelial cells and platelets, but absent in plasma.
Furthermore, in several HFs, AE13 immunostaining was detected in the matrix, whereas it was absent in the IRS, where it was physiologically expressed.These results show that miR-24 overexpression in ORS produces an altered differentiation process in HF keratinocytes.
Therefore, in our model, the SREBP-SCAP complex can be either present in the ER if the cholesterol level is high, or absent if the cholesterol level is below the physiologically relevant threshold, a situation that occurs following its dissociation from Insig.
Moreover, orthologs of the V. cholerae norspermidine biosynthetic pathway are absent from B. subtilis, confirming that norspermidine is not physiologically relevant to biofilm function in this species.
Truog and Fackler [ 5] argue that this is more physiologically integrative than brainstem reflexes such as pupillary constriction, which must be absent in WBD patients.
Although it is possible that the effect on neuronal differentiation is specific to Bim, the difference between Bim and Puma can also be explained by the fact that Bim is physiologically expressed and detectable in the neurogenic regions of the brain, whereas Puma may be absent unless transcriptionally induced during stress-induced apoptosis.
Physiologically, an appreciable percentage of Eskimo people have the B blood type (ABO system), which seems to be absent from other indigenous American groups.
Individual abdominal and esophageal pressure signals were accepted for analysis if they were timed at end expiration with no major cardiac artefact, if stable and physiologically acceptable end-expiratory pressure was present, and if active abdominal muscle contraction or esophageal contraction during the stimulation was absent.
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