Sentence examples for physiological setting from inspiring English sources

This model allowed us to characterize the phenotypic changes that occurred after TCR-mediated signaling in self-reactive thymocytes prior to their deletion in a highly physiological setting.

The liver represents a remarkable physiological setting where cAMP-responsive signaling plays a major role.

Additionally, the physiological setting and psychological attitude modulate the impact of environmental parameters.

The initial setting was set according to clinical parameters, and the second setting was adjusted with measurement of esophageal pressure (physiological setting) to optimize patient effort.

The physiological setting improved the duration and quality of sleep, decreased episodes of apnea, and the amount of inefficient efforts for ventilator triggering [18].

The direct visualization of protein kinase activity in living cells provides a genuine assessment of the efficacy and selectivity of these inhibitors in a physiological setting.

The CD4 T cell response to epitope M133 is of particular interest because it may be pathogenic, protective or regulatory, depending upon the physiological setting.

To confirm the microtubule-binding role of Sec61β in a physiological setting, we monitored the levels of ER stress in C. elegans upon the expression of various Sec61β constructs.

It is also important to consider that the radius and ulna act as a unit in the physiological setting and that it may be more biologically relevant to evaluate them together [56].

Those models may facilitate efforts to improve therapeutic outcomes for malignant melanoma by providing a platform for the investigation of cytotoxic treatments and tailored therapies in a more physiological setting.

For example, the analysis of the state of activity of ERs in the physiological setting of the estrous cycle has provided compelling evidence that hormone-independent mechanisms are responsible for activating ERs in non-reproductive organs.