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"The physiological examples are compelling but without being able to determine the chain of custody, that's the key to confirming the use".
Physiological examples of these interactions are discussed.
However, numerous physiological examples can be cited where weak forces function as amplifiers.
Although mRNA can be cap methylated in cell extracts in vitro [ 42], physiological examples of post-transcriptional cap methylation have not been reported.
There are many physiological examples in which the extent of nuclear accumulation rather than the simple presence or absence of a protein in the nucleus is a key driver, such as in developmental processes or signal transduction and so these novel vectors may prove quite useful even before complete specificity is achieved.
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A physiological example of this type of mismatch in cutthroat x steelhead hybrids was documented by Hawkins and Foote [46], who observed incongruence between paternally conferred rates of egg development and maternally conferred yolk size in hybrid offspring.
Thus, the CUL3Δ403 459 mutation is a novel physiological example of the importance of this CRL rigidity and to our knowledge the first example of a human mutation that impedes the scaffolding function of a Cullin.
We chose the antibody-secreting capacity of plasma cells, normally characterized by chronic activation of the UPR and high levels of XBP1s expression, as a physiological example to confirm the role of RTCB in XBP1 mRNA splicing in vivo.
In biology, there are many macro-physiological examples of homeostatic control using negative feedback, for example the control of blood sugar level using insulin and glucagon.
We inflict major stress - be it pharmacological (for example, with catecholamines), physiological (for example, by excessive rehabilitation or over-rapid weaning), and psychological - through unnecessary pain and discomfort, sleep deprivation, anxiety, boredom, and communication failure.
Since many hemodynamic measurements result from interacting mechanical and physiological processes, examples of mathematical descriptions of hemodynamics have been constructed with a systems approach in mind.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com