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Taken together, these results indicate that small RNA silencing is not a physiological contributor to the IFN-mediated cellular response to virus infection.
We propose that the level of (SH 2Trx-ASK1 (inASK1-signalosome) may be a physiological contributor to the Klotho-mediated regulation of aging or longevity.
However, increased heart rate is the major physiological contributor to the rise in cardiac output necessary to meet the metabolic demands of exercise, the capacity for which is substantially reduced in both HFpEF and HFrEF.
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In real, non-anesthetized patients, other physiological contributors to metabolic needs, such as digestion, pain, discomfort, stress, inflammation, increased work of breathing, and so on, additionally increase this heterogeneity.
Altogether, our observations reveal anabolic glycogen metabolism in neurons as a key contributor to physiological aging.
We know surprisingly little about the pathobiology of COPD airway disease, though small airway fibrosis and obliteration are likely to be the main contributors to physiological airway dysfunction and these features occur earlier than any subsequent development of emphysema.
Little is known about the contributors and physiological responses to white matter hypoperfusion in the human brain.
All EFM are not equal contributors to physiological cellular states, and this approach may open a direction towards a broader identification of physiologically relevant EFM among the very large number of stoichiometrically possible modes.
Strength, a physiological factor was an important contributor to disability and satisfaction.
The rather large ~50% improvement in land-based shuttle-run performance observed in the two swim-training groups, but not in the control group, strongly indicates that physiological adaptations are a major contributor for the augmented exercise capacity observed during both shuttle runs and swim tests.
Behavior, energy availability, and physiological state are all important contributors to reproductive success and survival.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com