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There is a growing molecular and clinical evidence of immune impairment or immunoparalysis (IP in critically ill patients.IP could be a physiological attempt to return to homeostasis after an intense pro-inflammatory phase and would explain the prevalence of nosocomial and opportunist infections,in critically ill patients initially considered as an immunocompetent patients.
The EMT is a crucial process in the development of different tissues in the embryo and its reactivation in the adult may be regarded as a physiological attempt to control inflammatory responses and to 'heal' damaged tissue.
This specific methylative inactivation of apoptotic and antiproliferative genes might instead mirror a physiological attempt to counter the state of pseudo-hypoxia, induced by SDH dysfunction and described in Pollard et al. (2005) and Cervera et al. (2008).
It might be proposed that the predominant and specific upregulation of the Mcl-1 protein at t = 24 hours within the early phase of post-hemorrhage recovery contributes to a physiological attempt, thus acting against the potential risk of immunosuppression following HS.
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This protective function explains why higher AIs may be found in tumours than in normal tissue, as these elevated AIs may indicate physiological attempts to eliminate the genetic alterations that are frequently found in neoplastic cells.
Techniques that combine a transverse directed force to the physiological technique attempt greater influence on biomechanical properties.
Similar task designs could be used in physiological studies attempting to generate linking hypotheses between psychometric and neurometric functions, ultimately allowing changes in perceptual sensitivity to be linked to changes in an underlying neural substrate.
In order to demonstrate that the loss of normal GSK-3β activity results in disturbances of physiological measures, we attempted to determine whether sleep wake architecture, circadian rhythms of core body temperature and activity were altered in transgenic mice overexpressing GSK-3β activity specifically in the brain.
When the biliary tree is damaged by chronic inflammation, the physiological response is attempted repair through cholangiocyte proliferation (Tavoloni and Schaffner, 1985).
In the presence of impaired NO bioavailability, the endothelium implements various physiological pathways in the attempt to compensate for NO deficiency.
In response to a stressor such as pesticide exposure, the fish undergo a series of biochemical and physiological changes in an attempt to compensate the challenge imposed on them and thus cope with the stress.
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