Exact(16)
For every mumbler in the team line-ups come Friday evening, the man staring silently at a patch of turf a few feet in front of him, there will be an Alun Wyn Jones: wild-eyed and roaring, arms physically binding him to his team-mates as Hen Wlad Fy Nhadau binds him to those singing with similar passion in the stands.
One potential mechanism promoting similar evolutionary rates of physically binding proteins could be similar fractions of residues involved in protein-protein binding.
Whether, rP8 provides this protection by virtue of an anticomplement activity or by physically binding to spirochetes and shielding the spirochetes from complement attack remains to be examined.
Proteins often perform their functions through physically binding with other partners.
ChIP-chip data contain information about physically binding interactions, while TF knock-out experiments provide information about functional relations.
Recently, researchers have confirmed that most proteins perform their functions through physically binding to other proteins, permanently or transiently.
Similar(44)
To determine whether the in silico identified LEF-1/TCF binding sequences physically bind to the β-catenin/Lef-1 complex in vitro, we conducted a competitive electrophoretic mobility-shift assay (EMSA) with a radioactively labeled consensus LEF-1/TCF strong binding probe (CD1TOP [35]) and duplex oligonucleotides covering the potential sites in target promoters.
While tubulins have previously been found to physically bind Gα-subunits [29], [30], binding of Hsc70-3 to a G protein has not been reported before.
Outside-in signaling by αIIbβ3 is positively regulated by talin, which physically binds to the β3 tail through a phosphotyrosine binding domain (PTB) [19], and Src [12].
Binding of the flavonoid to MtbHadAB can physically occlude binding of the fatty acid into the substrate binding channel (Fig. 6A).
The data demonstrate that GRHL2 physically binds at gene promoters of EDC and other GRHL2 target genes, and such binding leads to alter gene promoter activity.
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