Sentence examples for physical remodelling from inspiring English sources

And it is this activity which ultimately results in the physical remodelling of synapses that is the fundamental mechanism by which brains develop and learn things.These discoveries will not be easy targets for drugmakers.

Developmental genes tended to have the highest bias towards day 7, possibly indicating a physical remodelling of the gill as a part of the acclimation process to the new zinc level.

CAFs are associated with tumour cells at all stages of cancer, and they support cancer progression by secreting chemokines, growth factors and various extracellular matrix (ECM) components, including collagen I 3 4 5. CAFs are also responsible for the physical remodelling of the ECM and the subsequent dissemination of tumour cells from the primary tumour 6.

This drastic physical remodeling of the cellular compound involves a remarkably fast concerted displacement.

Epigenetic changes involve the physical remodeling of chromatin structure that in turn regulates accessibility to transcription factors.

To our knowledge this is the first time that physical remodeling of the substrata has been identified as a mechanism for stigmergic self-organization of bacterial communities.

Enhanced contractility that attends this protein's expression is believed to be important in allowing these cells to contract while bound to matrix collagens and other proteins, thereby allowing for physical remodeling of the matrix itself [ 11].

As discussed above, the mammary gland undergoes dramatic physical remodeling after lactation and many of the steps required for this process provide an ideal environment for breast cancer growth and progression.

Our data show that normal mast cells overexpressing miR-9 exhibit markedly increased HSPE expression, supporting the assertion that miR-9 may promote the metastatic phenotype by enhancing the proteolytic activity of a number of proteases important in physical remodeling of the extracellular matrix and activate mediators responsible for cell dissemination.

But Tony was physically remodelled.

Implantable tissue engineering constructs could thus be seen not only as physical, possibly remodel able supports for cell adhesion and migration, but also as sophisticated delivery systems for the molecules that bear the signals.