Several different approaches have previously been employed in an attempt to identify biomarkers for SMA in both mouse models and patient cohorts, incorporating a range of physical, functional and molecular readouts [ 19, 21- 23].
Had Elena been used, Henry's last words would have read: TACTIL, VARIABLE POINT: "A text should reveal the heart's emotional condition, as an EKG readout reveals its physical one".
This was possible using the deep n-well, available in triple well technology, as a sensing electrode and placing, in the same physical area, part of the readout electronics.
It also uses no fragile proteins or lipid bilayers but provides a reliable solid-state platform with only physical tools for control and readout of the DNA.
Instead of a digital readout, there are actually physical empty/full indicators.
In the cabin, there are touchscreens for infotainment readout, along with standard physical controls for additional cabin control options.
All aspects of the experimental setup, such as the physical geometry, magnetic fields, and sensitive detector readouts, as well as control of the physics simulations, such as physics processes, interaction models and kinematic limits, are defined at runtime.
Next, also the effects on clinically relevant functional readouts, such as muscle function and physical activity were investigated.
In a typical physical experimental instrument, such as a fusion or particle physical application, the readout system generally implements an interface between the data acquisition (DAQ) system and the front-end electronics (FEE).
