Exact(5)
As expected, eGFR was lower in the high phosphate category.
There was no consistent trend towards a worse cardiovascular risk profile in the high versus low phosphate category.
The number of cardiovascular deaths was low in each phosphate category, and the lowest incidence rate was found among patients with phosphate 1.30 1.49 mmol/L.
Compared to the category with phosphate 0.90 1.09 mmol/L (n = 912), the high phosphate category (phosphate ≥1.50 mmol/L; n = 177) was characterised by more women (58.2 % vs. 44.8 %) and a higher percentage of persons residing in the lowest SIMD quintile areas (33.3 % vs. 30.9 %).
Follow-up time is given as median (interquartile range) When age, sex and eGFR were adjusted for, the all-cause mortality risk was increased by 275%% (hazard ratio [HR] 2.75; 95 % confidence interval [CI] 1.89 4.00) in the highest phosphate category compared to reference.
Similar(55)
Baseline characteristics were assessed according to the phosphate categories.
In Model 2, SIMD quintiles, phosphate categories, age sex and eGFR were entered into the same model.
Differences in incidence rates across the phosphate categories were tested for by a normal test with continuity correction.
The estimates for both the SIMD quintiles and phosphate categories were essentially unchanged when these variables were entered into the same model (Model 2).
The SIMD quintiles and phosphate categories, respectively, were adjusted for sex, age and eGFR in two separate models, Model 1a and 1b.
Differences in baseline characteristics across these phosphate categories were assessed using one-way ANOVA, Kruskall-Wallis test and Jonckheere-Terpstra trend test and Chi square test as appropriate, and P for linear trend was reported.
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