Sentence examples for phenotypic variant from inspiring English sources
To report a phenotypic variant of lattice corneal dystrophy associated with two missense changes, Ala546Asp and Pro551Gln, in the transforming growth factor-β-induced gene (TGFBI).
Mouse passaging has been proposed as a technique to eliminate less fit phenotypic variant subpopulations that may emerge during prolonged in vitro cultivation [30].
Higher melanin concentrations confer increased fitness to the AS strains, supporting the operational definition of adaptation that 'it is a phenotypic variant that results in the highest fitness among a specified set of variants in a given environment [13].
Selection, under stress, in following generations of a somatically induced phenotypic variant may also allow the co-selection of a corresponding germ line mutation thus making it apparently heritable such as phenotypic variant (Fig. 1).
In a subanalysis, we found no substantial difference between the phenotypic variant chronic lymphocytic leukemia and other NHL types and therefore report the pooled results.
In a human whole-blood killing assay, the LH/HC phenotypic variant showed a higher survival index than the HH/LC variant at 2 different inocula (p = 0.03).
Moreover, we also aim to obtain allelic series of independent mutations in the same gene, where related phenotypic variants would strongly associate the phenotype with the gene, thereby avoiding the necessity for a lengthy backcrossing scheme.
The use of mutagenesis in invertebrates to generate phenotypic variants has a long and productive history.
We explored the role of insertion sequences (IS), which are considered as driving forces for novel genotypic and phenotypic variants in prokaryotes.
This concept of relaxed selection provided Ford with a cause for the increase in observations of rare phenotypic variants in large and growing natural populations.
Riedl didn't think that this pattern is just because selection was sorting the phenotypic variants, but that it mirrored the mutations, namely that mutational pattern was structured by the internal developmental constraints.
