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The implemented developmental mechanisms of such systems are generally based on an abstraction of observed principles in biology and can be divided into two main categories: phenotypic mechanisms and genetic control mechanisms: Phenotypic mechanisms are those parts of the models that are used to represent the developing shape or behavior.
For example, simulating biological phenotypic mechanisms such as polarity and chemotaxis can yield a system with the ability to grow functional shapes [15] but does not per se imply predictive power for the evolution of development of biological organisms.
D. montana populations seem to be evolving multiple barriers to gene flow in allopatry and our study lays the groundwork for future investigations of the genetic and phenotypic mechanisms underlying these barriers.
These analyses can therefore be useful for both identifying the specific environmental factors (e.g. water availability) likely responsible for natural adaptive diversification and narrowing the possible underlying phenotypic mechanisms (candidate traits) involved.
In this manuscript, we directly tested this hypothesis and uncover that EAAT1 had an important role in the phenotypic mechanisms derived from the loss of TBPH function in the glia.
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Perhaps these aneuploidies provide a mechanism akin to genetic assimilation ('phenotype precedes genotype'), in which cells are provided with a phenotypic mechanism that facilitates survival until a more stable and/or less costly mechanism is attained.
This interpretation of a relatively late effect of GCs on endocrine differentiation would also dictate that the exocrine observations are either secondary or in parallel rather than part of an endocrine exocrine phenotypic switch mechanism.
These bacterial subpopulations provide a phenotypic resistance mechanism whereby a subset of cells with reduced metabolic activity, known as persisters, is tolerant to antibiotic treatment, which usually target growth processes like cell-wall, protein, and nucleic acid synthesis.
Microorganisms in biofilms show novel phenotypic characteristics, specific mechanisms to attach to surfaces and respond to the external signals.
[2] Staufner C, Haack TB, Kopke MG, Straub BK, Kolker S, Thiel C et al. Recurrent acute liver failure due to NBAS deficiency: phenotypic spectrum, disease mechanisms, and therapeutic concepts.
Future reciprocal transplant experiments should shed light on the different response mechanisms (phenotypic plasticity and/or adaptation) under different selection regimes relative to landscape and latitude.
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