The curcumin concentration decrease from the plasma appeared for the pulmonary administration to be in two distinct phases with an initial rapid elimination occurring in the first hour followed by a slower elimination from 1 to 8 h.
The second phase begins with an initial multiple alignment using the landmarks found in the first phase.
One instructional strategy to address stress effects is to use a phased approach with an initial learning phase under minimum stress, followed by gradual increasing exposure to stress more consistent with real-world conditions [31].
Several lesions (P3, P5, P8, P12) exhibited typical two-phase curves with an initial accumulation phase reaching a maximum at around 24 48 h, thus at a later time point than the liver peak.
Hence, two signal vectors in the phase space with an initial separation of δ Z0 will eventually diverge at a rate given by: δ Z t ≈ e λ t δ Z 0, (8).
Further, reciprocal changes in firing probability between lateral and central medial amygdala neurons have been reported in cats [46]: Auditory stimulation caused firing probabilities of lateral and central medial neurons to oscillate in phase opposition, with an initial excitation in LB and inhibition in CM.
Importantly, whereas the NAADP response in control cells was small and monophasic, that in SpTPC1- and SpTPC2-expressing cells was biphasic an initial "pacemaker" rise followed by an explosive Ca2+-release phase, with a longer initial Ca2+ release for SpTPC1 than SpTPC2.
The study employed a two-phase experimental design with an initial baseline phase followed by an alternating treatments phase, and was first conducted at a private school (School A) and subsequently replicated at a public school (School B).
When the react period was changed into 5-hour aerobic followed by a reduced 3.0 hour anoxic, a marginal improvement of SCOD removal in aerobic phase (77.27%) and anoxic phase (96.07%) with an initial SCOD of 1023.22 mg/L was observed due to enhanced aeration time.
On the other hand, when the react period was subsequently changed to 3.0 hour, aerobic period followed by 5.0-hour anoxic period, a marginal decrease of SCOD removal in aerobic phase (65.64%) and anoxic phase (86.07%) with an initial SCOD of 1042.52 mg/L was obtained due to lag of aeration time.
