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Assuming rates of clinical remission of 60% in the budesonide group and 30% in the placebo group at the end of the 12-month double-blind phase, with a sample size of 86 in the intention-to-treat (ITT) analysis (34 patients up to the interim analysis, 52 patient subsequently), the study had 80% power to yield a statistically significant result (one-sided α=0.025).
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The hand cohort study will be conducted in 5 phases with a sample of people, aged 50 years and over, registered with two local general practices.
We abstracted data from the first and third groups; bThis study included a control phase with routine CXRs, an evaluative phase with a small convenience sample of patients with routine CXRs in which the investigators studied the impact of routine CXRs on patient management, and a post intervention phase with no routine CXRs.
Cultures were sampled for cell counts and toxin analysis at the onset of dark phase, at the onset of light phase, and at 2-h intervals until the beginning of the next dark phase, with a sterile tube-sampling system [ 56, 57].
In the familiarity phase, participants were presented with a sample speech file followed by the series of rating questions, thus illustrating the experiment procedure and giving them the opportunity to report any problems and/or concerns.
This technique can also provide quantitative phase information of a sample with a spatial resolution of tens of nanometers [ 38- 41].
Alternatively, the NCO can contain only one LUT for storing the sine values and use a 90° phase offset (accessing the LUT with a sample offset) to generate the cosine values.
Assuming an intra-subject correlation of 0.5, we have powers above 99% to detect any of the group, phase, and group*phase interaction effects with a sample size of 100 per treatment arm and a 5% level of significance.
The sample was centrifuged in the same conditions for 4 min. The organic phase was again removed, leaving the aqueous phase with the sample, which was then desiccated on a vacuum centrifuge.
To calculate the circular variance we start with a sample of phases (phi_{i}), (i = 1,dots,N), in this case the phases collected to produce the phase difference density plots.
In the second phase, the NMP-Q was validated with a sample of 301 undergraduate students.
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