Sentence examples for phase of sensitization from inspiring English sources

The present study was designed to determine how 5-HT1B receptor ligands affected the development or the expression phase of sensitization to the amphetamine-induced locomotor response in mice.

During the phase of sensitization, B lymphocytes of the conjunctiva produce IgE against the allergen, which will link to mast cells.

As pointed out by Prescott [ 31], it is important to distinguish the induction and expression phases of sensitization.

The assay measures the proliferation of lymphocytes during the induction phase of skin sensitization and provides EC3 values (effective concentration for a stimulation index of threefold in lymphocyte proliferation compared to vehicle controls) to make comparisons of the relative potency of different chemical sensitizers.

This gradient effect may be due to either the acute phase of central sensitization, characterized by hyperalgesia extending outside the area of direct inflammation [ 46], or a gradient in local inflammatory mediators.

Studies on the initial phase of allergic sensitization show that a transient low-level IgE (the atopic antibody) response to inhalant antigen occurs in normal children, with those who do not develop allergy down-regulate it in the first years of life [ 82- 84].

The 5-HT1B receptor ligands affected similarly the behavioral response to the challenge dose of amphetamine on day 10 (ca. 55 110% more potent than the response to its first administration) when they were combined with the psychostimulant during the development phase (days 1 5) of sensitization.

As the underlying neuropharmacological mechanisms and anatomical substrates are considerably different between different drugs and different phases of behavioral sensitization, this study was designed to investigate the roles of the medial prefrontal cortex in the induction and expression of morphine-induced behavioral sensitization in mice.

In Ming et al. (2002), this behavior was thought to occur as a result of alternating phases of receptor sensitization and desensitization.

Several studies have shown that the VTA is related to the development phase of drug-induced sensitization [ 14].

It has been hypothesized that hypoxia causes release of an endothelium-derived constricting factor, but no such factor with the requisite characteristics has been positively identified; whilst endothelin 1 and others may play a role in HPV, possibly by providing the endogenous equivalent of pretone, they have been excluded as the mediator of Phase 2 Ca2+ sensitization.