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More aggressive and earlier treatment leads to a rapid phase of improvement (a J-shaped curve) and subsequent stabilisation after one year [ 24].
There definitely seems to be a "honeymoon" phase of improvement in QoL for patients, but there seems to be a drift downward in their scores after this.
KYG-180, the compound to come out of the nonlibrary-driven phase of improvement has about the same affinity for MMP-14 as KYG-172 (KD values of 11 and 7.6 μM, respectively), but is significant smaller in size and perhaps possesses more drug-like features.
Similar(55)
The Westchester Arts Council is beginning a second phase of improvements to its historic home in White Plains.
The first phase of improvements, replacing all the electronics and communications at the array, is not expected to cause any interruption in observations.
"The next phase of improvements will be challenging for Foxconn because they involve major changes in the working environment that will inevitably cause uncertainty and anxiety among workers.
The first phase of improvements, expected to begin in June 2002, will involve renovating the existing building on 165th Street and the Grand Concourse to make the glass facade more inviting and to upgrade the interior.
The first phase of improvements between Cardiff Bay and the city centre are predicted to cost £18m.
The council said Pauline Pilkington will leave in autumn after overseeing the first phase of improvements.
The planned electrification of Dunblane/Alloa services will also not be delivered in this phase of improvements.
The 20th century saw two major phases of improvement.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com