Sentence examples for phase of clearance from inspiring English sources
The increased size of the dimer (∼106 kDa vs. ∼25 kDa for a scFv) results in a prolonged serum half-life in vivo, with t1/2 of the beta phase of clearance increasing from 3.5 h for a typical scFv to 93 h for a scFv-Fc fusion in mice.
In the first phase of clearance, during the mid-1970s, 298 houses were demolished.
The half-life of the radiolabel in blood was short but there was a prolonged second phase of clearance with a half-life of about 40 h.
After an initial rapid phase of clearance from the CSF, the elimination of amyloid-β peptide1 40 was slower when this peptide was moving through the subarachnoid/cisternal spaces to be eventually retained around pial arteries and arterioles.
When measuring GFR from Cr-EDTA clearance through slope-intercept techniques, sampling is restricted to the second phase of clearance, and systematic errors introduced into the GFR values thus derived must be corrected.
The time course of total blood Hg concentrations was best described by a two-compartment model; that is, the disposition kinetics are biphasic, with a rapid initial phase followed by a slower terminal phase of clearance.
MyD88 appears to affect both the early, macrophage-independent phase of microbial clearance and the late, macrophage-dependent clearance phase.
In patient AR2, relatively high levels of tetramer+ CD4+ T cells (0.12%) and significant T cell proliferation were present during the phase of viral clearance.
However, for routine clinical practice, sampling is usually restricted to the second phase of the clearance, with the slope intercept method commonly used for the determination of GFR.
Techniques of limited sampling restricted to the slow exponential phase of radioisotope clearance provide a reasonable compromise to avoid the complexity of measuring GFR using the biexponential method where multiple blood samples need to be taken at earlier time points.
With the effective immune response to HPV, most infections had cleared by 6 months as observed in the trial participants, meaning that there are no data describing the early phase of the clearance process.
