For I + F, the crash reduction factors were 29%, 15 % and 21 for improving signal visibility, left turn phase improvement and left turn lane installation, respectively.
Due to the high symmetry of icosahedral viruses, NCS averaging is a very powerful option for phase improvement and phase extension (Kleywegt and Jone 1996).
(B) Plot of figure-of-merit-weighted (FOM) mean phase errors (wMPE) calculated relative to the subsequently refined structure for the various steps of phase improvement.
Open phase improvement was unlikely due to prophylactic treatment changes because in four out of six responders, this treatment was stopped, dose-decreased or unchanged.
In the acute phase improvement does not seem correlated to addition of Verapamil, which is likely more useful in preventing reapparition of attacks shortly after steroid discontinuation.
Further prime-and-switch phase improvement was achieved by returning to step 2. The whole procedure can be performed iteratively, until the extended phases are good enough for map interpretation.
(Phase combination step, PHSCMB) 5) Further prime-and-switch phase improvement was achieved by returning to step 2. The whole procedure can be performed iteratively, until the extended phases are good enough for map interpretation.
The subsequent phase improvement was performed by using RESOLVE [23].
In each phase, improvement was statistically significant (P < 0.05).
Model building and phase improvement were accomplished using ARP/wARP (36, 37).
In the second experimental and execution phase, improvement plans and care pathways are implemented, and coordination mechanisms are arranged.
