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It would thus appear that the level of pol-prim subunit is not usually rate-limiting during S phase entry.
The releasing E2F activates the transcription of genes necessary for S phase entry and progression [17].
For the multiple-dose trial phase entry criteria included measurable tumors of greater than 3 cm in the longest diameter.
Cell growth is necessary but not sufficient for S phase entry and the two processes are closely co-ordinated [24].
In cell lines, FoxM1 deficient cells exhibit delayed S phase entry, aneuploidy, polyploidy and can't complete mitosis.
For the dose-escalation phase, entry criterion was an externally measurable tumor (>2 cm in the longest diameter) that was amenable to surgical resection.
Similar(30)
S-phase entry was measured using BrdU incorporation assays.
pRb then activates E2Fs and allows S-phase entry.
SKP2 is of particular interest, as it plays a key role in S-phase entry [43].
BrdU assays were performed to measure the percentage of cells undergoing S-phase entry [31].
Ectopic overexpression of Id2 promotes S-phase entry in smooth muscle cells [16].
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