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Moreover, attention should be paid to the role of pharmacotherapy (for example, corticosteroids), which could influence the endocrine response to stress [ 65].
The effect of pharmacotherapy (for example, corticosteroids and biologicals) on neuroendocrine and immune responses to stress in these populations is unclear.
The main contribution, however, is often to assess the appropriateness of the pharmacotherapy; for example, according to general recommendations or with the use of indicators such as the Medication Appropriateness Index (MAI) 5 or Beers criteria 6.
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In clinical practice, suboptimal pharmacotherapy is common; for example, treatment with inappropriate drugs or dosages and/or omissions of drugs from which the patient would probably benefit 1.
For example, pharmacotherapy consultations given by hospital pharmacists on the wards can be monitored by recording the number of advices given to the physicians and nurses.
For example, aggressive pharmacotherapy may lead to an increased incidence of hypoglycaemic episodes, and the associated sympathetic activation may in turn increase the risk of CVD events.
For example, medical management plus pharmacotherapy with naltrexone generated similar outcomes to more expensive counseling approaches, even when counseling was performed once weekly and on an outpatient basis (Anton et al. 2006; O'Malley et al. 2003).
Organisational risks refer to ward characteristics, for example the extent to which pharmacotherapy guidelines or protocols are available and the level of existing knowledge and education.
For example, small molecule-based approaches, pharmacotherapies, RNA interference, viral vector-mediated gene therapy, stem cell therapies and immunotherapy.
Quitline advisers should therefore assess actively recruited smokers' nicotine dependence and tailor advice accordingly; for example, by encouraging use of pharmacotherapies 18.
For example, lithium, which is the mainstay pharmacotherapy, has well-documented effects on the circadian clock, and at least two clock mutant mice show a mania-like phenotype.
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