Indeed, medical, pharmacological, perishable, immobilization materials, etc, should be available in case of need when attending patients within the range of emergencies the ICUs are devised for.
To experimentally test the predictions of our model, we used a half-embryo assay to investigate whether levels and half-life of NICD were elevated under conditions where clock gene oscillations were robustly delayed using a pharmacological approach (see 'Materials and methods'; Gibb et al., 2009).
43 The mechanism of action of moxibustion combines thermal, radiation and pharmacological effects of the materials used, acting on the meridian system.
The general mechanism of moxibustion is proposed to be a combination of thermal (infrared radiation) and pharmacological action of the materials used [ 12, 13].
In order to study the assembly of autophagosomes in cells exposed to these materials or pharmacological stimuli, we used a stable transfected THP-1 cell line to study the formation of GFP-LC3 labeled autophagosomes by confocal microscopy.
While fully understanding the immunological and pharmacological properties of individual materials, the proper use of various delivery systems and adjuvants is necessary considering their benefits of enhancing vaccine immunogenicity and risks of adverse reactions induced by undesirable immune responses against autoantigens.
With limited amount of biopsy material available, detailed genetic and pharmacological evaluation of the primary material may not be feasible and, rapid measurement of Caspase-8 activity in primary cells derived from such samples in response to TRAIL may provide a solution.
Therefore, it is difficult to assess the pharmacological impact of the material or to standardize the extract for further development.
In order to exploit the by-product generated in the process of atemisinin extraction from A. annua L. our research group was prompted to study pharmacological activities of that material.
Investigation of pharmacological activities of the test materials revealed promising anti-inflammatory (ZO, PPF, and AL), analgesic (CUR and PPF), antipyretic (CUR and AL), antihypertensive (ZO and AL), and anti-ulcer (CUR, ZO, and AL) activities.
