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Nilotinib crosses the blood brain barrier and shows pharmacological effective levels in brain.
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Radiotherapy (RT) is a well-established non-pharmacological effective treatment for the alleviation of pain from spinal metastases [ 5, 6].
Standard pharmacological agents effective in FMS are also effective in this model; however, differing from FMS [ 75] opioids reduce the hyperalgesia in the cold-stress model.
Given the similar pathologies and histopathological changes, we hypothesized that the pharmacological treatments effective in nephrotoxity induced by external beam radiation might also mitigate [177Lu]-DOTATATE induced nephrotoxicity.
So the pharmacological agents effective for the treatment of inflammatory diseases may also be employed in cervical cancer.
Therefore, we raised the following questions: (1) Are non-pharmacological therapies effective and efficacious for patients with FC? (2) If so, are non-pharmacological therapies safe for patients with FC?
Next to non-pharmacological interventions, effective acute and preventive treatments play an important role [8].
Research is also needed on effective pharmacological and non-pharmacological interventions.
Reducing the frequency of these recurrent events by enhancing the uptake of effective pharmacological and non-pharmacological interventions should therefore be considered an important health care priority.
Understanding the signalling pathways and molecular targets through which TP exerts its effects may lead to the development of more effective pharmacological interventions.
Jane Brody's column "Trying to Break Nicotine's Grip" (Personal Health, May 20) recommends nicotine replacement therapy as an effective pharmacological treatment for smoking cessation.
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