Sentence examples for pharmacological development from inspiring English sources

Greater understanding of steroid biosynthesis has underpinned rational drug design and pharmacological development of potent and specific aromatase inhibitors (AIs).

Overall, compound 7, a potent and selective dual AChEI, can be considered as a candidate with potential impact for further pharmacological development in Alzheimer's therapy.

Taken together, these preliminary findings suggested that the compounds with the strongest bioactivity deserves further investigated for pharmacological development in AD therapy.

Overall, these cyanopyridine triazine hybrids can be considered as a candidate with potential impact for further pharmacological development in Alzheimer's therapy.

GPX therefore has potential therapeutic value as an antioxidant, but its pharmacological development has been limited because GPX uses a selenocysteine as its catalytic group and it is difficult to generate selenium-containing proteins with traditional recombinant DNA technology.

Overall, compound 8, is a permeable potent and selective dual AChEI that can be considered as a good candidate with potential impact for further pharmacological development in Alzheimer's therapy.

With preclinical experiments we are only at the beginning to study these issues, which are increasingly important in the light of new pharmacological developments targeting CGRP and its receptors by antagonists or monoclonal antibodies, and keeping in mind possible risks of a long-term treatment with these substances.

Thus, an atlas of DUB alterations in human cancer might provide an important tool to direct future pharmacological developments.

These considerations, together with novel pharmacological developments, have led to the increased use of low molecular weight heparins (LMWHs) as alternative antithrombotic agents in critically ill patients.

54 With respect to pharmacological developments, in recent years there has been increasing interest in the use of d-cycloserine (DCS) as a potential augmentation strategy for CBT for OCD.

The conclusion was that innovation in surgery inevitably follows a pathway with important differences from that followed by pharmacological developments, and that a different approach to evaluation is therefore needed.